Consistently, the findings of a further immunohistochemical study involving 134 patients with PAAD revealed that FAP was expressed in both stromal fibroblasts (98/134, 73.1%) and cancer cells (102/134, 76.1%), with expression being significantly associated with patient age (p < 0.001), tumor size (p < 0.001), fibrotic foci (p = 0.003), and perineural invasion (p = 0.009) (4), thereby highlighting the importance of FAP in the clinicopathological characterization of PAAD. The gene discussed is FAP; the disease is cancer.