In this study, we first obtained the expression pattern of RNF157 in PCa from multiple online databases, including GEPIA (http://gepia.cancer-pku.cn/), UALCAN (http://ualcan.path.uab.edu/index.html) and ENCORI (http://starbase.sysu.edu.cn/index.php). Here, RNF157 is linked to posterior cortical atrophy.