CEACAM5 and neoplasm: On univariate analysis, pathological T stage (P < 0.001), pathological N stage (P < 0.001), AJCC TRG grade (P = 0.001), pre-NCRT CEA level (P = 0.017), MPA score (P < 0.001), NLR score (P < 0.001), MLR score (P < 0.001), PNI score (P = 0.005), ALI score (P = 0.001), nerval invasion (P = 0.006), and tumor differentiation (P = 0.002) were independently associated with DFS in patients with LARC after NCRT and TME (Table 3).