GSTM2 and inborn error of immunity: Then, we performed GSEA on GSTM2 to search the pathways GSTM2’s probably participating in, and the enrichment results showed that GSTM2 were most associated with immune related biological processes and pathways, such as chemokine signaling, leukocyte transendothelial migration, IgA production, Th1 and Th2 cell differentiation, primary immunodeficiency, adaptive immune response, B cell activation, defense response, immunoglobulin binding, and antigen binding (Figures 5C–F).