LGALS9 and large cell neuroendocrine carcinoma: Multivariate Cox regression analysis showed that Gal-9 on tumor cells was the independent prognostic feature in LCNEC (HR = 1.818; 95% CI: 1.022-3.234, P = 0.042) and the risk score consisted of five immune protein markers (HR = 4.49; 95% CI: 2.415-8.347, P <0.001) was significantly independently related to prognostic prediction (Table 2).