Through Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis of sequencing results, Wnt signaling pathway and cell molecules adhesion (CAMs) were the most enriched signaling pathways (Figure 1F and 1G), and CRISP3 was the most significantly up-regulated gene in tumor tissues and closely related to tumor progression and metastasis. The gene discussed is CRISP3; the disease is neoplasm.