METTL14 and bacterial infectious disease: Specifically, Jian et al. discovered that METTL14 aggravates endothelial inflammation by enhancing the levels of m6A in forkhead box transcription factor (FOXO)1 mRNA 18; Wu et al. showed that m6A restrains inflammation by interacting with DNA histone modification 19; and Du et al. reported that METTL14 inhibits acute bacterial infections by exerting negative feedback control of SOCS1 20.