ITGB3 and nasopharyngeal carcinoma: The intracellular free iron (Fe2+) fluorescent indicator Phen Green SK, whose fluorescence was quenched by iron, showed that ITGB3 knockout and RSL3 treatment triggered an increase in intracellular free iron (Fe2+) levels in NPC cells, which was reversed upon P-EVs treatment and ITGB3 overexpression (Figure 3H and Figure S3C).