HSPB8 and head and neck squamous cell carcinoma: Six genes, namely heat shock protein B 8 (HSPB8), epidermal growth factor receptor (EGFR), integrin alpha-3 (ITGA3), fas-associated protein with death domain (FADD), cyclin-dependent kinase inhibitor 2 A (CDKN2A), and PINK1-Parkin RBR E3 ubiquitin-protein ligase (PRKN), were used to establish a risk model, which proved the practical value of these six genes in predicting HNSCC prognosis.