The secondary evaluation outcomes were alterations in blood urea nitrogen (BUN), uric acid (UA), estimated glomerular filtration rate (eGFR), urinary AKI biomarkers, renal fibrosis biomarkers (transforming growth factor-β1 (TGF-β1), connective tissue growth factor (CTGF)), and traditional Chinese medicine (TCM) symptoms. Here, CCN2 is linked to renal fibrosis.