A 2018 study shows that the loss of AKAP1 promoted mitochondrial fission due to reduced Drp1 phosphorylation at Ser637, localized Drp1 to the brain mitochondria and exacerbated stroke in a murine model of transient cerebral ischemia (Flippo et al., 2018). Here, AKAP1 is linked to transient ischemic attack.