When queried for “OXTR” of approx. 24,000 samples from 31 registered studies, the cancer biology database cBioportal identified 20 exonic missense mutations and one truncation at the end of exon 3 (Figure 1A; Cerami et al., 2012; Gao et al., 2013), all of which have been associated with different types of sarcoma/carcinoma/glioma (for a complete list see Supplementary Table 1). Here, OXTR is linked to central nervous system cancer.