Due to the lack of information regarding immunogenicity in breast milk in lactating women after the application of vaccine platforms based on viral vectors (Sputnik V and ChAdOx1-S) or inactivated viruses (BBIBP-CorV), we evaluated the presence of specific IgA and IgG anti-SARS-CoV-2 in maternal blood and breast milk of vaccinated lactating participants without prior infection and convalescent lactating participants who were vaccinated with diverse vaccine platforms. Here, CD79A is linked to infection.