DSG3 and ulcer disease: Actually, one patient, a 68-year-old Japanese woman with a three-month history of painful oral ulceration, showed both anti-Dsg 1 and 3 IgG autoantibodies by ELISA, while the other one, an 85-year-old Japanese woman with a 15-year history of painful oral ulcerations, showed only IgG autoantibodies against Dsg3 by ELISA (15).