The bFGF is in the process of the formation of diffuse large B-cell lymphoma vascular specificity is high; it can effect on vascular proliferation factor, make use of tyrosinase in endothelial cells receptors on endothelial cells effectively, induce endothelial cell proliferation, and thus, promote the formation of blood vessels. The gene discussed is FGF2; the disease is diffuse large B-cell lymphoma.