PRP also releases hepatocyte growth factor and tumor necrosis factor-alpha, which possess potent anti-inflammatory effects [30] In this study, long-term improvements in the PRP group could be explained by the fact that PRP might have effects on improving all phases of tissue repair, e.g., inflammatory, proliferative, and remodeling phases of capsular healing in periarthritis [18]. The gene discussed is HGF; the disease is periarthritis.