MYCN and neuroblastoma: However, as most of our neuroblastoma cases are metastatic at presentation often with more than one image-defined risk factor, the FNAB weakness can be mitigated as an International Neuroblastoma Pathology Classification (the Shimada system) is not absolutely required for diagnosis in such cases.24,25,26 FNAB yielded valuable information about the n-myc status in three of our cases.