In addition, we examined the expression levels of CCKAR and CCK in pigmented nevus (n = 4; HMB-45 negative and Melan A positive) and blue nevus (n = 3; HMB-45-weakly positive and Melan A positive) and found no positively stained cells in all cases of pigmented nevus and blue nevus, as represented by one case of each nevus (Figure 1a). This evidence concerns the gene CCK and blue nevus.