NEAT1 and hereditary neoplastic syndrome: LncRNA NEAT1 (NEAT1), encoding two variants of Neat1_v1 (3.7kb) and Neat1_v2 (23kb), is transcribed from a gene locus called multiple endocrine tumor type 1 in familial tumor syndrome on chromosome 11, which abnormally expressed in many malignant tumors, including CRC [11].