One could speculate that these contradictory findings might be due to variations in animal species and age, bacterial dose or bacterial strain, duration of the course of infection, or that the generation of the lgt deletion mutant might have been performed differently in the reported studies, possibly underlying these divergent outcomes on lipidation and maturation of staphylococcal Lpp in murine staphylococcal sepsis. Here, LPP is linked to infection.