TLR2 and bacterial arthritis: In a mouse model of S. aureus septic arthritis, Lpps gave rise to pronounced arthritogenic effects in both NMRI and C57BL/6 wild-type mouse strains, whereas TLR2 deficient mice displayed no signs at all following intra-articular knee joint challenge with the purified Lpl1(+sp) (Mohammad et al., 2019).