Figures 3, 4 showed the decision tree models of IgG and IgA between IBS patients with persistent symptoms and HCs (Figures 3A, 4A), IBS patients with severe abdominal pain/discomfort and HCs (Figures 3B, 4B), IBS patients with severe symptoms and HCs (Figures 3C, 4C), IBS patients with severe anxiety and HCs (Figures 3D, 4D). This evidence concerns the gene CD79A and irritable bowel syndrome.