Additionally, IL-1, IL-6, IL-8, and TNF-alpha are released from neutrophils, macrophages, and lymphocytes.6 The pancreas is very sensitive to ischemia; therefore, it plays a crucial role in ensuring adequate blood flow, homeostasis, and preventing inflammatory conditions.7 The pathophysiology of AP, both experimentally and clinically, has not been clearly demonstrated. This evidence concerns the gene IL6 and alkaline phosphatase measurement.