LRPAP1 and myopia: To date, a total of three homozygous frameshift mutations in LRPAP1 have been found in fourteen patients with early-onset high myopia from nine unrelated families: c.863_864delTC (p.Ile288Argfs*118) (n = 10) [7, 8], c.605delT (p.Asn202Thrfs*8) (n = 3) [6], and c.199delC, (p.Q67sfs*8) (n = 1), as reported in our previous study [7].