Several of these pathways appeared to be related to the cancer or HNSCC pathways, including focal adhesion (p = 1.0E-5), small-cell lung cancer (p = 3.1E-4), ECM–receptor interaction (p = 4.6E-3), proteoglycans in cancer (p = 7.2E-3), and PI3K-Akt signaling pathway (p = 1.0E-2). The gene discussed is AKT1; the disease is head and neck squamous cell carcinoma.