We previously highlighted that m6A was critical in the progress of epithelial–mesenchymal transition (EMT) since Snail could be modified by m6A in the CDS region and METTL3/YTHDF1 could mediate the expression and translation of Snail mRNA to regulate cancer cells growth and metastasis (Fig. 5A) [101]. The gene discussed is METTL3; the disease is cancer.