MAP1LC3B and cardiovascular disorder: Furthermore, OE of GFP‐LC3B improved mitochondrial function and extended proliferation in HUVEC endothelial cells via activation of mitophagy (Mai et al., 2012), while mild enhancement of mitophagy can offer therapeutic benefits against cardiovascular disorders without damaging mitochondrial functionality and hence cardiomyocytes health (Ajoolabady et al., 2022).