A typical patient's preoperative and intraoperative information was inputted into the model, for example, age: 76 years, albumin: 33.2 g/L, ASTI: 4 days, CRP: 2.00 mg/L, IBL: 200 ml, IMBP: 115 mmHg, AIMBPD: 45 mmHg, smoking: No, alcohol: No, PD: Yes, hypertension: No, CCD: No. The model predicted that the risk of POD in this patient was 65.166%, indicating that the patient was at high risk of POD; indicating that medical staff should prepare for treatment and care in advance (Figure 8A). This evidence concerns the gene CRP and Hypertension.