ALDH2 and hypertensive disorder: Studies have suggested that the ALDH2*2 allele is an important risk factor for ischemic stroke in Taiwanese [23] and Korean [26] men, as well as in Chinese women (OR = 2.207, 95% CI 1.416–3.439)[22], since it increases dyslipidemia, hypertension, and diabetes, which may contribute to cerebral arteriosclerosis [27–29].