NUPR1 and hepatocellular carcinoma: In order to uncover the radioresistant mechanism of NUPR1 on HCC, RNA sequencing was performed and screened several upregulated (n = 263, FC > 1.5, P < 0.05) and downregulated (n = 269, FC < 0.67, P < 0.05) genes in LV-NUPR1 MHCC-97H cells compared with LV-NC cells.