In our study, we aimed to: (I) identify the relationship of SLC14A1 and PCa and verify the correlation between SLC14A1 and BCR using data obtained from the Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA) database; (II) predict the correlation between SLC14A1 and miRNAs, and find the miRNAs which are related to BCR using Pearson correlation analysis and Kaplan–Meier survival curves; (III) analyze the potential biological signaling pathway of PCa, which SLC14A1 might involves in, by Gene Set Enrichment Analysis (GSEA) and GO and KEGG Pathway Enrichment Analysis. The gene discussed is BCR; the disease is posterior cortical atrophy.