Interestingly, IGF2BP2 targets had a significantly higher proportion of negative log2(fold change) values than non-IGF2BP2 targets, implying that knockdown of IGF2BP2 globally and preferentially inhibited the expression of IGF2BP2 target genes in lung cancer cells upon IGF2BP2 knockdown (Fig. 4A, B). This evidence concerns the gene IGF2BP2 and lung cancer.