To elucidate the underlying mechanism by which IGF2BP2 affects the growth and survival of lung cancer cells, we employed the RNA-seq technology to reveal potential pathways altered upon IGF2BP2 knockdown in lung cancer cells, given the fact that IGF2BP2 is an m6A reader, essential for the stability, location and translation of target RNAs [14], with high-likelihood on transcription regulation. This evidence concerns the gene IGF2BP2 and lung carcinoma.