Moreover, increased neurotoxicity caused by increased levels of toxic cytokines (e.g., IL-1β, IL-6, IL-8, TNF-α, and IFN-γ) and chemokines (e.g., CCL11, CCL2, CXCL8, and CXCL10) is significantly associated with the G-CoDe and the schizophrenia phenome [5]. This evidence concerns the gene IL1B and schizophrenia.