Importantly, using 2 TMA sets, each containing 80 HCC and their adjacent normal tissues (LVC1607 and LVC1608), and 1 TMA set that contained 160 HCC, 32 ICC, and 8 normal cases (D2000601), IF analysis showed that while GS and p-4EBP1 (T37/46) were more uniformly expressed in the normal tissues, their expression varied drastically in the HCC samples (Figure 9E). The gene discussed is EIF4EBP1; the disease is hepatocellular carcinoma.