The definition of a probable case used by WHO is that of a “person presenting with an acute hepatitis (non A-E) with serum transaminase >500 IU/L (AST [aspartate aminotransferase] or ALT [alanine aminotransferase]), who is 16 years and younger, since 1 October 2021)”.2 Cases with a known alternative explanation for their presentation are excluded. The gene discussed is GPT; the disease is Acute hepatitis.