DNAJB6 has been previously linked to neurodegenerative diseases via its function in protein folding and the clearance of polyglutamine stretches (polyQ), Gillis et al., 2013; Hageman et al., 2010 and to muscular dystrophy via its protein-protein interaction with Bag3 in the sarcomere Sarparanta et al., 2012. This evidence concerns the gene BAG3 and neurodegenerative disease.