To gain insight into this question, we performed a comparative scRNA-seq transcriptomic analysis by combining our previously published scRNA-seq data of GP66+ CD4+ T cells isolated from LCMV Armstrong-infected mice on day 10 post infec (Khatun et al., 2021) with our current dataset of GP66+ CD4 T cells from day 10 post-LCMV Cl13 infection. This evidence concerns the gene CD4 and infection.