Interestingly, and similar to our analysis on the T cell repertoire for GP66-specific CD4+ T cells during acute LCMV Armstrong infection, we did not observe any clonal overlap between M1 and M2 when α and β chain CDR3 sequences were paired on a per cell basis, although a few instances of TCR CDR3 overlap were observed when considering either α and β chain CDR3 sequences individually (Figure 1B). This evidence concerns the gene CD4 and infection.