A high level of MIP mRNA was associated with poor OS in all histological subtype gastric cancer patients, HR = 1.55 (1.29–1.86)[32] and all ovarian cancer patients, HR = 1.15 (1.01–1.31),[33] but better RFS in all histological subtype breast cancer.[34] The expression of MIP is extremely low in the kidney, and the biological performance of MIP in ccRCC has not yet been studied. The gene discussed is MIP; the disease is breast cancer.