AQP6 was found to be expressed at lower levels in clear cell renal cell carcinoma (fold change = −8.330, Yusenko renal, −4.140, Gumz renal), papillary renal cell carcinoma (fold change = −2.013, Jones renal, −5.431, Yusenko renal), renal Wilms tumor (fold change = −3.621), and renal pelvis urothelial carcinoma (fold change = −1.750) versus corresponding normal samples. This evidence concerns the gene AQP6 and clear cell renal carcinoma.