AH levels of TNF-α (P = .0076), MMP-2 (P < .0001), VEGF (P = .0227), IFN-γ (P = .0013), MCP-1 (P = .0294), basic fibroblast growth factor (bFGF) (P = .0029), platelet-derived growth factor-AA (PDGF-AA) (P = .0017), TIMP-1 (P < .0001), LT-α (P = .037) in the CACG group were significantly greater than in the POAG group. The gene discussed is TNF; the disease is open-angle glaucoma.