The mean concentrations of TNF-α (P = .02), IL-6 (P = .0012), IL-8 (P = .0023), VEGF (P = .0417), and IFN-γ (P = .011) were significantly lower in the CACG than those in the APAC group. The gene discussed is CXCL8; the disease is aldosterone-producing adrenal cortex adenoma.