Killer cell immunoglobulin-like receptor 3DL1 (KIR3DL1) and KIR3DL3, members of the killer cell immunoglobulin-like receptor (KIR) family, are NK and T cell subset modulators that protect target cells by inhibiting NK cell activation.[42,43]KIR3DL1 expression may be involved in the pathogenesis of BD, VKH, and AS.[44–46]KIR3DL3 is considered a susceptibility gene that is associated with BD. The gene discussed is KIR3DL3; the disease is Behcet disease.