SIGLEC15, PDCD1LG2(PD-L2), TIGIT, PDCD1(PD-1), CD274(PD-L1), CTLA4, LAG3, and HAVCR2(TIM3) are transcripts related to immunological checkpoints that perform vital functions in tumor immune evasion. The gene discussed is PDCD1LG2; the disease is neoplasm.