As shown in Fig. 9A, the expression levels of PIK3CA (P < 0.05) and PTEN (P < 0.001) were higher in CESC patients with high-risk scores than those with low-risk scores in TCGA database, while the expression levels of TP53 were lower in high-risk scores than low-risk scores. This evidence concerns the gene PTEN and cervical squamous cell carcinoma.