To prove this conclusion, we used the Kaplan ⁃Meier Plotter database to analyze the prognosis of CRC patients based on the expression level of SELENBP1 in the relevant immune cell subgroups, and found that patients with high SELENBP1 mRNA expression level in the CD4+ T cell high-infiltration group, eosinophil high-infiltration group, Th1 cell high-infiltration group and Th2 cell high-infiltration group had longer OS. This evidence concerns the gene CD4 and colorectal carcinoma.