We then tested the lung carcinoma cell lines A549 (WT EGFR) and H1975 (T790M EGFR), the immortalized breast epithelial line MCF10A and parental CHO cells that lack EGFR expression with cSNX1.3, cPTD4 control, or Sapitinib (Fig. 4E–G and Supplementary Fig. 1B, C). The gene discussed is EGFR; the disease is lung carcinoma.