Similarly, CD6 pQTLs colocalized with any stroke genetic associations; CD40 pQTLs colocalized with the genetic associations for any stroke, any ischaemic stroke and large artery stroke; TMPRSS5 pQTLs colocalized with any stroke, any ischaemic stroke and cardioembolic stroke genetic associations. Here, TMPRSS5 is linked to ischemic stroke.