Exosomal miR‐522 from CAFs inhibits the expression of arachidonate lipoxygenase 15 (ALOX15), an inhibitor of ferroptosis, in gastric cancer cells, leading to reduced accumulation of lipid‐ROS in cancer cells and ultimately a decreased sensitivity to chemotherapy.[163] CAFs transfer functional miR‐196a to head and neck cancer cells through exosomes and exosomal miR‐196a targets ING5 and CDKN1B to confer cisplatin resistance. Here, ALOX15 is linked to head and neck cancer.