AKT1 and esophageal squamous cell carcinoma: MiR‐208a can be transported by exosomes and forced expression of miR‐208a induces radioresistance via targeting p21 and activating the Akt/mTOR pathway in lung cancer cells.[96] Similarly, Chen et al. demonstrate that hypoxic cancer cell‐derived exosomal miR‐340‐5p confers radioresistance in esophageal squamous cell carcinoma (ESCC) by targeting KLF10/UVRAG axis.