Interestingly, the detection of 10 mRNAs in plasma exosomes of NSCLC patients could predict icotinib therapy response.[88] Xiao et al. suggest that FTO, an N6‐methyladenosine RNA demethylase, is remarkably increased in serum exosomes of patients with gefitinib resistance. This evidence concerns the gene FTO and non-small cell lung carcinoma.