The analysis in this part showed that the set of 20 high-score genes contains 12 genes related to prostate cancer (mTOR, PTEN, P27, NKX3.1, TP53, EP300, AR, KRAS, PIK3CA, KMT2D, APC, ARID1A). The gene discussed is KMT2D; the disease is Familial prostate cancer.