Companion diagnoses, such as MSI, ERBB2 staining, EGFR, BRAF, ALK fusion, and BRCA1/2, can be done before the standard treatment, which is another reason why the CGP test is not needed, as the drivers of lung cancer, colon cancer, and melanoma are already known to a certain extent. The gene discussed is BRAF; the disease is colonic neoplasm.