CD274 and diffuse large B-cell lymphoma: Mean Isa maximum plasma concentration (Cmax) and area under the concentration versus time curve over 1 week (AUC1 week) were, respectively, 226 μg/ml and 22,500 μg.h/ml in the cHL anti‐PD‐1/PD‐L1 naïve cohort, 265 μg/ml and 26,600 μg.h/ml in the cHL anti‐PD‐1/PD‐L1 progressors cohort, 253 μg/ml and 23,700 μg.h/ml in the DLBCL cohort, and 181 μg/ml and 15,000 μg.h/ml in the PTCL cohort (Table 5).