LSS and early-onset non-syndromic cataract: Abnormal mutational expression of the LSS gene caused congenital cataracts (OMIM# 616,509) (Zhao et al. 2015), APMR4 (OMIM#618,840) (Romano et al. 2018; Besnard et al. 2019), and autosomal recessive hypotrichosis (OMIM# 618,275) (Romano et al. 2018).