Due to the higher levels of testosterone in male than female, it has been hypothesized that testosterone might be a promoter of SARS‐CoV‐2 infection and progression in males, considering the regulatory effect of androgen receptor (AR) and testosterone on the transcription of a transmembrane protease serine 2, which is a critical factor enabling cellular infection by coronaviruses, including SARS‐CoV‐2 (Peckham et al., 2020; Pozzilli and Lenzi, 2020; Cattrini et al., 2020). The gene discussed is AR; the disease is infection.