Furthermore, consistent with dcSSc phenotype, silica-exposed patients had higher ATA positivity (21.8% vs. 14.8%), lower ACA positivity (28.3% vs. 39.5%), higher prevalence of ILD (38.3% vs. 30.0%), and were more likely to be treated with cyclophosphamide (CYC) and/or MMF (14.9% vs. 8.3%), albeit statistical significance was not reached. The gene discussed is ATM; the disease is interstitial lung disease.